Ginger - Herbal Research
A WHO Organization resource - Full Report
Medicinal uses supported by clinical data
As a mild sedative and sleep-promoting agent (8, 12, 22–25). The drug is often used as a milder alternative or a possible substitute for stronger synthetic sedatives, such as the benzodiazepines, in the treatment of states of nervous excitation and anxiety-induced sleep disturbances (22–25).
Uses described in pharmacopoeias and in traditional systems of medicine
As a digestive aid, and an adjuvant in spasmolytic states of smooth muscle and gastrointestinal pains of nervous origin (8, 12). When associated with papaverine, belladonna, and other spasmolytics, Radix Valerianae has been shown to be useful as an adjuvant in spastic states of smooth muscle such as spastic colitis (8).
Uses described in folk medicine, not supported by experimental or clinical data
To treat epilepsy, gum sores, headaches, nausea, sluggish liver, urinary tract disorders, vaginal yeast infections, and throat inflammations; and as an emmenagogue, antiperspirant, antidote to poisons, diuretic, anodyne, and a decoction for colds (5, 8).
5. Pharmacopée française. Paris, Adrapharm, 1996.
8. Morazzoni P, Bombardelli E. Valeriana officinalis: traditional use and recent evaluation of activity. Fitoterapia, 1995, 66:99–112.
22. Leathwood PD, Chauffard F. Quantifying the effects of mild sedatives. Journal of psychological research, 1982/1983, 17:115.
23. Leathwood PD, Chauffard F. Aqueous extract of valerian reduces latency to fall asleep in man. Planta medica, 1985, 2:144–148.
24. Schultz H, Stolz C, Muller J. The effect of valerian extract on sleep polygraphy in poor sleepers: a pilot study. Pharmacopsychiatry, 1994, 27:147–151.
25. Balderer G, Borbely A. Effect of valerian on human sleep. Psychopharmacology, 1985, 87:406–409.